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Home :: Family Health :: Necrosis Necrosis - Necrosis symptom, treatment, causesNecrosis is due to the death of cells. an area of tissue, or part or all of an organ. Necrosis may result from inadequate blood supply, cutting off of the blood supply, injury, damage by extreme heat or cold, radiation, toxins produced by bacteria, or noxious chemicals. Necrosis is the name given to accidental death of cells and living tissue. This is a serious condition because the dead areas of bone do not function normally, are weakened, and can collapse. If the process involves the bones near a joint, it often leads to collapse of the joint surface. Although it can happen in any bone, avascular necrosis most commonly affects the ends (epiphysis) of long bones such as the femur, the bone extending from the knee joint to the hip joint. In contrast with apoptosis, cleanup of cell debris by phagocytes of the immune system is generally more difficult, as the disorderly death generally does not send cell signals which tell nearby phagocytes to engulf the dying cell. Blood supply to the bone can be temporarily interrupted or completely cut off for a number of reasons, but the most frequent cause is a broken bone (fracture). Your doctor might use other terms to describe avascular necrosis, such as osteonecrosis, aseptic necrosis or ischemic bone necrosis. In 33 to 72% of patients with nontraumatic avn disease is bilateral. Idiopathic avn of the hip affects men 4 to 5 times more often than women, with a peak incidence between ages 30 and 60. AVN of the knee is most common in elderly women. Each glomerulus (microscopic "filtering screen") has a tubule that transports urine to the ureters (see urinary system anatomy ) and metabolically alters the urine and its chemicals. Avascular necrosis of bone is a disorder in which an avascular (lacking in blood supply) area of bone undergoes necrosis (dies). AVN is not common, but it is encountered in a certain number of patients with lupus. his problem primarily affects younger adults. The goal for treatment of avnis to save the natural hip joint if possible and not to have to replace the affected femoral head with an artificial joint. In order to accomplish this, early diagnosis is very important. Other bones may also be affected by avn, but much less often than the hip. The amount of disability that results from avascular necrosis depends on what part of the bone is affected, how large an area is involved, and how effectively the bone rebuilds itself. Normally, bone continuously breaks down and rebuilds - old bone is torn away and reabsorbed, and replaced with new bone. In the course of avascular necrosis, however, the healing process is usually ineffective and the bone tissues break down faster than the body can repair them. If left untreated, the disease progresses, the bone collapses, and the joint surface breaks down, leading to pain and arthritis. Causes of NecrosisThe common Causes of Necrosis :
Symptoms of NecrosisSome Symptoms of Necrosis :
Treatment of Necrosis
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