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Galactorrhoea - Galactorrhoea symptom, treatment, causes


Galactorrhoea occurs due to the abnormal milk production by a woman who is not pregnant or breastfeeding; very rarely, by a man. Milk production is stimulated by the pituitary hormone prolactin, and galactorrhoea is most commonly due to excessive prolactin production by a benign tumour of the pituitary gland called a prolactinoma. Other causes include the use of certain drugs and hormonal disorders such as HYPOTHYROIDISM (deficiency of thyroid hormone).

In many cases there are no symptoms other than the galactorrhoea, though women with excessive prolactin often stop ovulating and menstruating, and may have symptoms of oestrogen deficiency such as hot flushes. If a prolactinoma exists, it may also cause headache and visual disturbances.

When excessive prolactin is found in the blood, the pituitary is examined by X-ray. CAT scan or magnetic resonance imaging (MRI) to check for a prolactinoma. The drug bromocriptine blocks prolactin production and will shrink most prolactinomas. If the tumour remains large, radiotherapy or surgery may be needed.

Galactorrhoea is the spontaneous flow of milk from the breast, unassociated with childbirth or nursing. The main cause is the excess production of prolactin, particularly if both breasts are secreting milk. Prolactin is a hormone secreted by the pituitary gland which stimulates the production of milk in the breasts. Galactorrhoea is sometimes known as Galactorrhoea- Hyperprolactinaemia but galactorrhoea is a physical finding whilst hyperprolactinaemia is a biochemical abnormality. Each can occur without the other. Certain drugs can cause galactorrhoea eg tranquillisers, the oral contraceptive pill, methadone. Galactorrhoea is inappropriate secretion from the breast between episodes of breast feeding or after weaning. It may also be used to describe excessive production of milk. Other causes include pituitary disease, renal disease, an underactive thyroid gland and sarcoid. In many cases there are no symptoms other than the galactorrhoea, though women with excessive prolactin often stop ovulating and menstruating, and may have symptoms of oestrogen deficiency such as hot flushes. Galactorrhoea is much more common in women than in men. In women it may be physiological but in men it is always pathological.

Causes of Galactorrhoea

The common causes and risk factor's of Galactorrhoea include the following:

  • Excess production of prolactin.
  • Certain drugs can cause galactorrhoea eg tranquillisers, the oral contraceptive pill, methadone.
  • Pituitary and renal disease.
  • Stress.
  • An underactive thyroid gland and sarcoid.

Symptoms of Galactorrhoea

Some sign and symptoms related to Galactorrhoea are as follows:

  • Inappropriate breast milk production .
  • Hot flushes.
  • Breast milk in non-pregnant non-breastfeeding woman.
  • Headache and visual disturbances.

Treatment of Galactorrhoea

Here is list of the methods for treating Galactorrhoea:

  • The drug bromocriptine blocks prolactin production and will shrink most prolactinomas.
  • Trans-spehnoidal surgery is a viable option. This may need to be combined with radiotherapy.

 


Galactorrhoea - Galactorrhoea symptom, treatment, causes

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