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Home :: Drugs :: Magnesium Sulfate


Magnesium Sulfate - Learn about Magnesium Sulfate Side Effects and Precautions

Magnesium Sulfate Information

The pharmacology action of Magnesium Sulfate is that magnesium has CNS depressant effect; prevents/controls seizures by blocking neuromuscular transmission and decreasing amount of acetylcholine liberated at end plate by motor nerve impulse. Orally it attracts/retains water in intestinal lumen, thereby increasing intraluminal pressure and inducing urge to defecate.

Magnesium Sulfate is used in treatment of hypertension, encephalopathy, and convulsions in children with acute nephritis; inhibition of premature labor; treatment of life-threatening ventricular arrhythmias; prevention and treatment of nutritional magnesium deficiency; laxative (oral).

Magnesium Sulfate Class Anticonvulsant/Electrolyte/Laxative
How Magnesium Sulfate Supplied Epsom Salt Granules see care instructions
Magnesium sulfate Injection
Brand Name : Magnesium Sulfate

Interaction and Contraindication of Magnesium Sulfate

Interaction of Magnesium Sulfate - Cardiac glycosides (eg, digoxin):  Administer magnesium sulfate with extreme caution because of serious changes in cardiac conduction, which can result in heart block, may occur if administration of calcium is required to treat magnesium toxicity.
CNS depressants (eg, barbiturates, narcotics):  Possible additive CNS depressant effects.
Neuromuscular blocking agents:  Potentiation of neuromuscular blockade.
Nitrofurantoin:  Decreased absorption of nitrofurantoin (oral magnesium).
Penicillamine:  Reduced penicillamine effects (oral magnesium).
Tetracyclines:  Decreased absorption of tetracyclines (oral magnesium).

Contraindication of Magnesium Sulfate - Toxemia of pregnancy during 2 hr preceding delivery; MI; myocardial damage; heartblock

Side Effects o f Magnesium Sulfate

Here are the list of some common side effects ofMagnesium Sulfate :

  • Cardiac depression; circulatory collapse; hypotension; cardiac arrest
  • CNS depression; depressed reflexes; muscle weakness; flaccid paralysis
  • Hypocalcemia.
  • Respiratory paralysis
  • Flushing; sweating; hypothermia

Precaution and Warning while taking Magnesium Sulfate

The precaution and warnings of Magnesium Sulfate drug is as follows:

  • Explain name, action, and potential side effects of drug.

How to store Magnesium Sulfate

  • Store granules and injection at ambient room temperature (59° to 86°F).

 
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