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Ketoprofen - Learn about Ketoprofen Side Effects and Precautions

Ketoprofen Information

The pharmacology action of Ketoprofen is that it decreases inflammation, pain, and fever, probably through inhibition of cyclooxygenase activity and prostaglandin synthesis.

Ketoprofen is used in treatment of rheumatoid arthritis, osteoarthritis, mild to moderate pain, primary dysmenorrhea. Sustained-release form only:  Treatment of rheumatoid arthritis and osteoarthritis. OTC Use:  Temporary relief of minor aches and pains associated with common cold, headache, toothache, muscular aches, backache, minor arthritis pain, menstrual cramps, and reduction of fever.

Interaction and Contraindication of Ketoprofen

Interaction of Ketoprofen - Anticoagulants:  Increased risk of gastric erosion and bleeding.
Aspirin:  Additive GI toxicity.
Cyclosporine:  Nephrotoxicity of both agents may be increased.
Lithium:  Serum lithium levels may be increased.
Methotrexate:  Increased methotrexate levels.

Contraindication of Ketoprofen - Patients in whom aspirin, iodides, or any NSAID have caused allergic-type reactions

Side Effects o f Ketoprofen

Here are the list of some common side effects ofKetoprofen :

• Peripheral edema; fluid retention; CHF
• Headache; dizziness; lightheadedness; drowsiness; vertigo
• Rash; pruritus.
• Visual disturbances; stomatitis
• Peptic ulcer; GI bleeding; dyspepsia; nausea; diarrhea; constipation; abdominal pain; flatulence; anorexia; vomiting
• Bronchospasm; laryngeal edema; rhinitis; dyspnea

Precaution and Warning while taking Ketoprofen

The precaution and warnings of Ketoprofen drug is as follows:

• Warn patient not to take aspirin or other NSAIDs.
• Caution patient to report changes in stool (eg, color, consistency, frequency), fluid retention and shortness of breath.
• Instruct patient to report the following symptoms to health care provider: skin rash, itching, visual disturbances, weight gain, edema, black stools, or persistent headache.
• Advise patient that drug may cause drowsiness and to use caution while driving or performing other tasks requiring mental alertness.
• Caution patient to avoid exposure to sunlight and other sources of ultraviolet light and to use sunscreen or wear protective clothing to avoid photosensitivity reaction.

How to store Ketoprofen

• Do not crush capsules.
• Administer with food, milk, or antacids to minimize GI upset.
• Store at room temperature in tightly closed, light-resistant container.