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Home :: Drugs :: Gemfibrozil


Gemfibrozil - Learn about Gemfibrozil Side Effects and Precautions

Gemfibrozil Information

The pharmacology action of Gemfibrozil is that it decreases blood levels of triglycerides and VLDL by decreasing their production. Also decreases cholesterol and increases HDL.

Gemfibrozil is used treatment of hypertriglyceridemia in adult patients with type IV or V hyperlipidemia that presents risk of pancreatitis and does not respond to diet; reduction of coronary heart disease risk in type IIb patients who have low HDL levels (in addition to elevated LDL and triglycerides) and have not responded to other measures.

Gemfibrozil Class Fibric acid derivative
How Gemfibrozil Supplied Lopid Tablets 600 mg
Brand Name : Apo-Gemfibrozil , Gen-Gemfibrozil , Novo-Gemfibrozil , Nu-Gemfibrozil , PMS-Gemfibrozil

Interaction and Contraindication of Gemfibrozil

Interaction of Gemfibrozil - Lovastatin:  Increases risk of rhabdomyolysis.
Oral anticoagulants (eg, warfarin):  Anticoagulant effect may be increased

Contraindication of Gemfibrozil - Hepatic or severe renal dysfunction, including primary biliary cirrhosis; preexisting gallbladder disease.

Side Effects of Gemfibrozil

Here are the list of some common side effects of Gemfibrozil :

  • Atrial fibrillation
  • Fatigue; vertigo; headache.
  • Eczema; rash.
  • Blurred vision.
  • Dyspepsia; abdominal pain; diarrhea; nausea; vomiting; constipation; acute appendicitis.

Precaution and Warning while taking Gemfibrozil

The precaution and warnings of Gemfibrozil drug is as follows:

  • Inform patient of need to restrict dietary intake of fats; teach patient dietary restrictions to follow.
  • Emphasize importance of the following increased cardiac risk factors: smoking, alcohol consumption, lack of exercise.
  • Instruct patient to report the following symptoms to health care provider: abdominal pain, persistent nausea and vomiting, bleeding, and irregular heartbeat.
  • Advise patient that drug may cause dizziness or blurred vision and to use caution while driving or performing other tasks requiring mental alertness

How to store Gemfibrozil

  • Administer 30 min before breakfast and supper.
  • Store at room temperature in a tightly closed container
  • pression.

 

 
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