Gallium Nitrate- Learn about Gallium NitrateSide Effects and Precautions

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Gallium NitrateInformation

The pharmacology action of Gallium Nitrateis that it exerts hypocalcemic effect by inhibiting calcium resorption from bone, possibly by stabilizing bone matrix, thereby reducing increased bone turnover.

Gallium Nitrateis used in Treatment of symptomatic, cancer-related hypercalcemia unresponsive to adequate hydration

Gallium NitrateClass

Hypocalcemic agent

How Gallium NitrateSupplied

Ganite Injection 25 mg/mL

Brand Name :

Gallium Nitrate

Interaction and Contraindication of Gallium Nitrate

Interaction of Gallium Nitrate- Nephrotoxic drugs (eg, aminoglycosides, amphotericin B): May increase risk for development of renal insufficiency.

Contraindication of Gallium Nitrate- Severe renal impairment (serum creatinine more than 2.5 mg/dL).

Side Effects of Gallium Nitrate

Here are the list of some common side effects of Gallium Nitrate:

Tachycardia; lower extremity edema; asymptomatic hypotension

Lethargy, confusion, dreams, hallucinations, paresthesia

Acute optic neuritis; visual impairment; tinnitus; decreased hearing

Nausea or vomiting; diarrhea; constipation

Mild to moderate transient hypophosphatemia (79%); decreased serum bicarbonate concentrations (50%); hypocalcemia

Hypothermia; fever; skin rash

Precaution and Warning while taking Gallium Nitrate

The precaution and warnings of Gallium Nitratedrug is as follows:

Advise patient or caregiver that medication will be prepared and administered by health care provider in a health care setting.

Review dosing schedule with patient or caregiver.

Advise patient to report any of the following to health care provider: abnormal dreams, chills, difficulty breathing, fast heartbeat, hallucinations, change in vision or hearing, weakness, mouth sores, muscle cramps or spasms, numbness or tingling around lips, abnormal skin sensations, confusion, constipation or diarrhea, swelling of ankles or feet, nausea, vomiting, rash.

How to store Gallium Nitrate

Do not administer if particulate matter or cloudiness is noted.

Discard unused portions of vial. Do not save any unused portions for future use.

Store unopened vials at controlled room temperature (68° to 77°F). Diluted solutions can be stored for up to 48 hr at ambient room temperature (59° to 86°F) or 7 days if stored under refrigeration (36° to 46°F).