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Home :: Drugs :: Darbepoetin Alfa
Darbepoetin Alfa - Learn about Darbepoetin Alfa Side Effects and Precautions
Darbepoetin Alfa Information
The pharmacology action of Darbepoetin Alfa
is that
it
stimulates red blood cell production.
Darbepoetin Alfa
is used in
treatment
of anemia associated with chronic renal failure, whether or not the patient is on dialysis. Treatment of anemia in patients with nonmyeloid malignancies where anemia is caused by coadministered chemotherapy
.
| Darbepoetin Alfa Class : |
Recombinant human erythropoietin |
| How Darbepoetin Alfa Supplied |
Aranesp Solution for injection 25 mcg/mL , Solution for injection 40 mcg/mL , Solution for injection 60 mcg/mL , Solution for injection 100 mcg/mL , Solution for injection 150 mcg/0.75 mL , Solution for injection 200 mcg/mL , Solution for injection 300 mcg/mL , Solution for injection 500 mcg/mL |
| Brand Name : |
Darbepoetin Alfa |
Interaction and Contraindication of Darbepoetin Alfa
Interaction of Darbepoetin Alfa -
Not available
Contraindication of Darbepoetin Alfa -
Uncontrolled hypertension; hypersensitivity to the active substance or the excipients
Side Effects of Darbepoetin Alfa
Here are the list of some common side effects of Darbepoetin Alfa :
- Thrombosis, CHF; cardiac arrhythmias; hypertension; hypotension; cardiac arrest; angina pectoris; cardiac chest pain; stroke; acute MI; transient ischemic attack.
- Headache; dizziness; seizure.
- Diarrhea; nausea; vomiting; abdominal pain; constipation
- Upper respiratory tract infection; dyspnea; cough; bronchitis.
- ; infection; myalgia; fever; chest pain; arthralgia; limb pain; back pain; peripheral edema; fatigue; injection site pain; fluid overload; access infection; flu-like symptoms; access hemorrhage; asthenia; death.
Precaution and Warning while taking Darbepoetin Alfa
The precaution and warnings of Darbepoetin Alfa drug is as follows:
- Explain name, dose, action, and potential side effects of drug. If patient or caregiver will be administering at home, review Information for Patients and Caregivers insert with the patient or caregiver. Ensure that the patient or caregiver understands how to store, prepare, and administer the dose, and dispose of used equipment and supplies.
- Remind patient that injection is administered once a week.
- Advise patient that dose will be adjusted based upon measured hemoglobin level.
- Advise patient to continue to follow their dietary and dialysis prescriptions while taking this medication.
- Advise patient to notify the health care provider immediately if any of the following occur: rash; hives; shortness of breath; swelling of the eyes, mouth, or throat; palpitations; severe headache; signs of infection (eg, fever, chills); swelling of feet or ankles; intolerable GI effects (eg, nausea, vomiting, diarrhea).
- Instruct women to notify health care provider if pregnant, planning on becoming pregnant, or breastfeeding.
- Instruct patient not to take any prescription or OTC medications or dietary supplements unless advised by the health care provider.
How to store Darbepoetin Alfa
- Do not administer if particulate matter, cloudiness, or discoloration are noted.
- Withdraw prescribed dose into syringe for injection. Do not dilute solution.
- Vials contain no preservative. Discard any unused portion. Do not combine unused portions.
- Administer via IV or subcutaneous route only.
- Do not administer in conjunction with other drug solutions.
- Prescribed dose is administered once weekly.
- Rotate subcutaneous injection sites.
- Dose will be slowly adjusted based on hemoglobin levels.
- Store vials in refrigerator (36° to 46°F). Do not freeze or shake. Protect from light
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